Response of seasonally anoestrous ewes to six-hour periods of GnRH infusion administered on six consecutive days |
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Authors: | McLeod B J Haresign W |
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Institution: | ARC Research Group on Hormones and Farm Animal Reproduction University of Nottingham School of Agriculture Sutton Bonington Loughborough, Leics. LE12 5RD, U.K. |
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Abstract: | Twelve seasonally anoestrous Clun Forest ewes were infused i.v. with either 500 or 1000 ng GnRH/h for 6 h on each of six consecutive days in early or mid-anoestrus. Plasma LH concentrations were elevated during each GnRH infusion but returned to pretreatment levels when infusion ceased. The response to the first infusion was significantly greater (p<0.001) than that to subsequent infusions. In addition, both a GnRH dose and a seasonal influence were evident in the LH response, but these failed to reach statistical significance. Although 7 12 ewes ovulated, only two produced functionally normal corpora lutea. |
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