Some Factors Involved in the Control of Microtubule Assembly in Sea Urchins |
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Authors: | BRYAN JOSEPH |
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Affiliation: | Department of Biology, University of Pennsylvania Philadelphia, Pennsylvania 19174 |
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Abstract: | Some recent evidence is discussed which suggests that the controlof microtubule assembly during the formation of the mitoticapparatus in sea urchins involves three factors. These include:nucleation sites such as the kinetochores, a mechanism for regulatingintracellular calcium, and a heat stable substance which preventsspontaneous, non-nucleated microtubule polymerization. |
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