呼吸机相关性肺炎鲍氏不动杆菌感染的临床特征分析

目的：研究呼吸机相关性肺炎鲍氏不动杆菌感染的临床特征。方法：选取2010 年1 月到2015 年1 月我院收治的应用呼吸机患者130 例，根据是否合并肺炎鲍氏不动杆菌感染将患者分为研究组（86 例）和对照组（44 例），分析呼吸机相关性肺炎鲍氏不动杆菌的临床特征，然后根据药敏实验选择应用药物进行治疗，并观察治疗效果。结果：呼吸机相关性肺炎鲍氏不动杆菌感染的分布科室主要以ICU 为主，大约为76.74％，神经外科次之，大约为8.14％；研究组呼吸机应用时间（18.72± 3.15）天显著长于对照组（6.18± 0.02）天，两组比较差异具有统计学意义（P＜0.05）；研究组经舒巴坦联合左氧氟沙星或者亚胺培南治疗后总有效率为91.86％。结论：呼吸机相关性肺炎鲍氏不动杆菌多发生于ICU，且感染者呼吸机应用时间较长，联合治疗效果显著。

Clinical Features of Ventilator-associated Pneumonia Infected with Acinetobacter Baumannii

Objective:To study the clinical features of ventilator-associated pneumonia infected with Acinetobacter baumannii.Methods:A total of 130 patients, who were admitted to Central Hospital of Jiading District from January 2010 to January 2015 and underwent ventilator, were divided into study group(n=86) and control group(n=44) according to whether or not infected with Acinetobacter baumannii . The clinical features of ventilator-associated pneumonia infected with Acinetobacter baumannii were analyzed. The study group was treated with drugs picked from the drug sensitive test, and the therapeutic effect was observed.Results:Patients with ventilator- associated pneumonia infected with Acinetobacter baumannii were mainly distributed in ICU, accounting for 76.74%; neurosurgery followed, accounting for 8.14%. Ventilator application time (18.72± 3.15 days) in the study group was significantly longer than that (6.18± 0.02, days) in the control group, the difference was statistically significant (P<0.05). The total effective rate of study group after treated with sulbactam plus levofloxacin or imipenem was 91.86%.Conclusion:Ventilator-associated pneumonia infected with Acinetobacter baumannii often appears in ICU, and the ventilator application time of patients is longer.The combined treatment has a remarkableeffect.