离子交换吸附L-色氨酸的研究

L-色氨酸是含吲哚环的芳香族氨基酸,也是人类必需的氨基酸之一,目前,工业上除部分采用化学合成法外,主要采用前体发酵法和酶促转化法生产。随着在医药、食品和饲料加工中应用的开拓,市场的需求量日益增加,色氨酸生产具有广阔的前途。

Study on Adsorption of L-tryptophan by Ion Exchange

Two cation exchangers were selected out for separating L-tryptophan from aqueous solution by comparing thrmodynamic and kinetic properties among fifteen ion-exchangers and adsorption resins. They had stronger adsorption capacity for L-tryptophan when pH was between 3 and 10. Dynamic test of cation exchanger showed that the saturattd adsorption capicity kept almost constants when the flow rate varied from 0. 04 to 0. 01 ml/ml - min. The adsorption efficiency achieved 99. 4% and the eluate was condensed 3. 68 times by using 1 mol/L ammonia solution at the flow rate from 0. 05 to ad-sorptin 0. 025 ml/ml - min. The total yield of L-tryptophan was 95% in the process.