The cream dilution gene, responsible for the palomino and buckskin coat colours, maps to horse chromosome 21 |
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| Authors: | M. M. Locke,L. S. Ruth,L. V. Millon,M. C. T. Penedo,J. D. Murray,& A. T. Bowling |
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| Affiliation: | Veterinary Genetics Laboratory, University of California, Davis, CA, USA. mmlocke@ucdavis.edu |
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| Abstract: | The colour locus historically referred to as C in the horse is linked to microsatellites markers on horse chromosome 21. Preliminary results demonstrated linkage of Ccr, thought to be the cream dilution variant of the C locus, to HTG10. An analysis of horse chromosome 21 using additional families confirmed and established a group of markers linked to Ccr. This work also improved the resolution of previously reported linkage maps for this chromosome. Linkage analysis unambiguously produced the map order: SGCV16-(19.1 cM)-HTG10-(3.8 cM)-LEX60/COR73-(1.3 cM)-COR68-(4.5 cM)- Ccr-(11.9 cM)-LEX31. Comparative and synteny data suggested that the horse C locus is not tyrosinase (TYR). |
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| Keywords: | buckskin coat colour cream dilution horse genetics microsatellite palomino |
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