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Inhibition of epidermal growth factor-induced cell transformation by tannins

Authors:	Nomura Masaaki Tsukada Hirotaka Ichimatsu Daisuke Ito Hideyuki Yoshida Takashi Miyamoto Ken-Ichi

Affiliation:	Department of Hospital Pharmacy, School of Medicine, Kanazawa University, 13-1 Takara-Machi, Kanazawa, Ishikawa 920-8641, Japan.

Abstract:

Keywords:	AP-1, activator protein 1 BME, basal medium Eagle DMSO, dimethylsulfoxide DTT, dithiothreitol EBV-EA, Epsten-Barr virus early antigen EGCG, (−)-epigallochatechin-3-gallate EGF, epidermal growth factor EGFR, EGF receptor ERKs, extracellular-signal regulated kinases FBS, fetal bovine serum JB6 P+, JB6 promotion sensitive cell line JB6 P−, JB6 promotion resistant cell line JNKs, c-JUN N-terminal kinases MAP, mitogen-activated protein MEM, minimum essential medium MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide PBS, phosphate-buffered saline PI3K, phosphatidylinositol 3-kinase TPA, 12-O-tetradecanoylphorbol-13-acetate UV, ultraviolet
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