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1H, 13C and 15N resonance assignment of phage T4 endoribonuclease RegB
Authors:Benoît Odaert  Fakhri Saïda  François Bontems
Affiliation:(1) ICSN-RMN, Ecole-Polytechnique (équipe CNRS), Palaiseau, 91128, France;(2) Present address: Institut Européen de Chimie et Biologie, Pessac, 33607, France;(3) Present address: Center for Molecular Genetics, University of California, San Diego, La Jolla, CA 92093-0634, USA
Abstract:RegB is involved in the control of the phage T4 life cycle. It inactivates the phage early mRNAs when their translation is no more required. We determined its structure and identified residues involved in substrate binding. For this, all backbone and 90% of side-chain resonance frequencies were assigned.
Keywords:RegB  mRNA inactivation  Translation initiation  Toxin-antitoxin modules  Ribosomal S1 protein
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