Unusual course of plasmocytosis. Contribution to the problem of extramedullary and asecretory forms

A case of plasmocytosis treated and observed for more than 4 years was characterized by an extraordinarily strong tendency to extramedullary manifestations and by a nearly asecretory course of disease. Its histomorphological explanation with regard to a differential diagnosis towards a possible secondary neoplasia was connected with many problems at the beginning of the disease when it had to be localized in the scull-face area as well as in the final stage. It may be assumed that this is one of those pictures of disease developing in the limiting area of the maturation zone ranging from the lymphoplasmacytoid cell type to the finally differentiated plasma cells and their systemic neoplasia. The term "plasmocytoma with an extra-osseous tumour expansion" will certainly correspond to its clinical picture in the best way.