Results of [131I]metaiodobenzylguanidine treatment in metastatic carcinoid. |
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| Authors: | M Bestagno C Pizzocaro R Pagliaini P L Rossini P Guerra |
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| Affiliation: | Nuclear Medicine Service, Spedali Civili, Brescia, Italy. |
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| Abstract: | The results obtained with [131I]metaiodobenzylguanidine (131I-MIBG) treatment in 6 patients affected by metastatic carcinoid are reported. 131I-MIBG was given in single doses of 3.7-8.0 GBq, reaching a maximum cumulative dose of 29.5 GBq in 4 courses. Objective responses were not observed, but in 4 cases an apparent stabilisation of the disease for more than 1 year was obtained. A subjective response regarding the carcinoid syndrome was observed in 4 cases. No response was seen in 2 cases. No adverse side-effects of any importance were observed, usually being prevented by a mild medication. |
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