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Silencing of enzymes involved in ceramide biosynthesis causes distinct global alterations of lipid homeostasis and gene expression
Authors:Ruangsiriluk Wanida  Grosskurth Shaun E  Ziemek Daniel  Kuhn Max  des Etages Shelley G  Francone Omar L
Affiliation:Department of Cardiovascular, Metabolic, and Endocrine Diseases, Pfizer Inc., Cambridge, MA, USA.
Abstract:
Keywords:serine palmitoyl transferase  dihydroceramide desaturase  ceramide  sphingolipids  human hepatocytes  lipidomic  microarray  LDL receptor  apoB secretion
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