Interchromosomal gene conversion as a possible mechanism for explaining divergence patterns of ZFY-related genes |
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| Authors: | Hidenori Hayashida Kei-ichi Kuma Takashi Miyata |
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| Institution: | (1) Department of Biophysics, Faculty of Science, Kyoto University, 606 Kyoto, Japan;(2) Department of Biology, Faculty of Science, Kyushu University, 812 Fukuoka, Japan |
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| Abstract: | Summary The divergence pattern of mammalian ZFY-related genes from human (ZFY and ZFX) and mouse (Zfy-1 and Zfx) was reexamined on the basis of nucleotide substitutions at the synonymous codon-alternating positions. It is possible to explain the unusual divergence pattern of the mammalian Y-linked ZF genes by interchromosomal gene conversion by X-linked ZF genes. Furthermore, the rates of evolution of mammalian X- and Y-linked ZF genes were shown to agree well with those expected from our model.
Offprint requests to: T. Miyata |
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| Keywords: | ZFY Sex chromosome Evolutionary rate Gene conversion |
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