MPSQ: a web tool for protein-state searching |
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Authors: | Zheng Siyuan Sheng Jia Wang Chuan Wang Xiaojing Yu Yao Li Yun Michie Alex Dai Jianliang Zhong Yang Hao Pei Liu Lei Li Yixue |
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Institution: | Bioinformatics Center, Key Lab of Systems Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China. |
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Abstract: | MPSQ (multi-protein-states query) is a web-based tool for the discovery of protein states (e.g. biological interactions, covalent modifications, cellular localizations). In particular, large sets of genes can be used to search for enriched state transition network maps (NMs) and features facilitating the interpretation of genomic-scale experiments such as microarrays. One NM collects all the catalogued states of a protein as well as the mutual transitions between the states. For the returned NM, graph visualization is provided for easy understanding and to guide further analysis. |
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