Institution: | 1. The Key Laboratory of Weak-Light Nonlinear Photonics, MOE, School of Physics and TEDA Applied Physics School, Nankai University, Tianjin, China;2. The Key Laboratory of Weak-Light Nonlinear Photonics, MOE, School of Physics and TEDA Applied Physics School, Nankai University, Tianjin, China
The 2011 Project Collaborative Innovation Center for Biological Therapy, Nankai University, Tianjin, China;3. Division of Medical and Biological Measurement, National Institute of Metrology, Beijing, China;4. The Tianjin Horimed Medical Technology Co., Ltd, Tianjin, China;5. Tianjin Eye Hospital, Nankai University affiliated Eye Hospital, Clinical College of Ophthalmology Tianjin Medical University, Tianjin, China |
Abstract: | As an important biomedical imaging method, endoscopic optical coherence tomography (OCT) is necessary to check its performance regularly. The ordinary plane phantoms are only able to evaluate part of image tangent to the probe. In this research, a spatial resolution estimate method of the endoscope OCT system is proposed. The annular phantom, made by uniformly distributing golden scattered microparticles in polydimethylsiloxane (PDMS), can provide dynamic scanning imaging evaluation of endoscopic OCT system, closer to its actual working status. The point spread function analysis method is used to analyze the imaging results of the annular phantom with the endoscopic OCT system. And many scattered particles are statistically analyzed to determine the spatial resolution of the endoscope OCT system. The method is low in cost, simple and convenient. It is valuable for the development of test standards for endoscope OCT systems.![image](/cms/asset/188e2054-be28-49e4-9bcc-e5e1a1804752/jbio202100035-gra-0001.png) |