Quantitative Assessment of Bacterial Adhesion to Eukaryotic Cells of Human Origin |
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Authors: | C. L. HARTLEY C. M. ROBBINS M. H. RICHMOND |
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Affiliation: | Department of Bacteriology, University of Bristol Medical School, University Walk, Bristol BS8 1TD, England |
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Abstract: | An in vitro system to measure the adhesion of bacteria to human, eukaryotic cells was devised. Adhesion indices for test strains of bacteria could be calculated. Significant differences were then observed between various strains of Escherichia coli from a variety of sources, in their ability to adhere. The possible applications of the test, especially for the routine screening of bacteria for adhesion and for inhibitors of attachment, were considered. |
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