Ischemia reperfusion injury induces pyroptosis and mediates injury in steatotic liver thorough Caspase 1 activation |
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Authors: | Kolachala Vasantha L Lopez Chrissy Shen Ming Shayakhmetov Dmitry Gupta Nitika Arora |
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Institution: | 1.Department of Pediatrics, Emory University School of Medicine, 1760 Haygood Drive, Atlanta, GA, 30322, USA ;2.Transplant Services, Children’s Healthcare of Atlanta, Atlanta, GA, USA ; |
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Abstract: | Apoptosis - A steatotic liver is increasingly vulnerable to ischemia reperfusion injury (IRI), and the underlying mechanisms are incompletely defined. Caspases are endo-proteases, which provide... |
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