Na+ and K+ channels: history and structure |
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| Authors: | Clay M Armstrong Stephen Hollingworth |
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| Institution: | 1. Department of Physiology, University of Pennsylvania, Philadelphia, Pennsylvania;2. Undergraduate Neuroscience Program, University of Pennsylvania, Philadelphia, Pennsylvania |
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| Abstract: | In this perspective, we discuss the physiological roles of Na and K channels, emphasizing the importance of the K channel for cellular homeostasis in animal cells and of Na and K channels for cellular signaling. We consider the structural basis of Na and K channel gating in light of recent structural and electrophysiological findings. |
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