Cola-Induced Hypokalemia-a Case Report and Review of the Literature |
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| Affiliation: | 1. Department of Endocrinology, SUNY-Downstate Medical Center, Brooklyn, New York;2. Department of Endocrinology, New York Harbor Health Care System, Brooklyn Campus, Brooklyn, New York;1. Endocrinology and Metabolism Institute, Cleveland Clinic Foundation, Cleveland, Ohio;2. Education Institute, Cleveland Clinic Lerner College of Medicine, Cleveland, Ohio;3. Yale Pediatric Endocrinology Department, Yale University School of Medicine, New Haven, Connecticut;4. Yale Department of Orthopaedics and Rehabilitation, Yale University School of Medicine, New Haven, Connecticut;5. Pathology and Laboratory Medicine Institute, Cleveland Clinic Foundation, Cleveland, Ohio;1. University of Maryland School of Medicine, Baltimore, Maryland;2. Baltimore Washington Medical Center Baltimore, Maryland;3. University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania;4. Boston University Medical Center, Boston, Massachusetts;1. Department of Orthopedic Surgery, Hadassah-Hebrew University Medical Center, Jerusalem, Israel;2. Maccabi Healthcare Services, Israel;3. Center for Clinical Quality and Safety, Jerusalem, Israel;4. Endocrinology and Metabolism Service, Hadassah-Hebrew University Medical Center, Jerusalem, Israel;1. Sapienza University of Rome Experimental Medicine Department Medical Physiopathology, Food Science and Endocrinology Section Food Science and Human Nutrition Research Unit |
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| Abstract: | ObjectiveWe aim to describe an unusual and underappreciated cause for hypokalemia.MethodsWe describe a patient diagnosed with cola-induced hypokalemia and review the literature.ResultsIngestion of massive amounts of cola can lead to severe hypokalemia through several pathophysiologic mechanisms. These perturbations include osmotic diarrhea, osmotic diuresis, and hyperinsulinemia secondary to hyperglycemia with resultant intracellular to cellular shifts in potassium. These effects are magnified by concomitant high levels of caffeine.ConclusionIngestion of large quantities of cola should be added to differential diagnosis for severe hypokalemia. (Endocr Pract. 2013;19:e21-e23) |
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