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FANCD2-associated Nuclease 1, but Not Exonuclease 1 or Flap Endonuclease 1, Is Able to Unhook DNA Interstrand Cross-links in Vitro
Authors:Julia Pizzolato  Shivam Mukherjee  Orlando D Sch?rer  Josef Jiricny
Institution:From the Institute of Molecular Cancer Research, University of Zurich and ;the Department of Biology, Swiss Institute of Technology (ETH) Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland, and ;the Departments of §Chemistry and ;Pharmacological Sciences, Stony Brook University, Stony Brook, New York 11794-3400
Abstract:
Keywords:DNA damage  DNA endonuclease  DNA repair  DNA-protein interaction  enzyme mechanism  exonuclease  interstrand cross-links
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