Simulation of daytime vigilance by the additive interaction of a homeostatic and a circadian process |
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Authors: | Peter Achermann Alexander A Borbély |
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Institution: | (1) Institute of Pharmacology, University of Zürich, Winterthurerstrasse 190, CH-8057 Zürich, Switzerland, CH |
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Abstract: | The two-process model of sleep regulation postulates that a homeostatic and a circadian process underlie sleep regulation.
The timing of sleep and waking is accounted for by the interaction of these two processes. The assumptions of two separate
processes or of a single process resulting from their additive interaction are mathematically equivalent but conceptually
different. Based on an additive interaction, subjective alertness ratings in a forced desynchrony protocol and subjective
sleepiness ratings in a photoperiod experiment were simulated. The correspondence between empirical and simulated data supports
the basic assumption of the model.
Received: 7 October 1993/Accepted in revised form: 22 January 1994 |
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Keywords: | |
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