SREBP2 regulates the endothelial response to cytokines via direct transcriptional activation of KLF6 |
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| Affiliation: | 1. Department of Pharmacology, Vascular Biology and Therapeutics Program, Yale University School of Medicine, New Haven, CT, USA;2. Department of Cellular and Molecular Medicine, The University of Arizona, Tucson, AZ, USA |
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| Abstract: | |
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| Keywords: | Endothelium inflammation nuclear receptors/SREBP cholesterol chemokines interferon 25HC" },{" #name" :" keyword" ," $" :{" id" :" kwrd0045" }," $$" :[{" #name" :" text" ," _" :" 25-hydroxycholesterol BHLHE40" },{" #name" :" keyword" ," $" :{" id" :" kwrd0055" }," $$" :[{" #name" :" text" ," _" :" class E basic helix-loop-helix protein 40 ChIP-seq" },{" #name" :" keyword" ," $" :{" id" :" kwrd0065" }," $$" :[{" #name" :" text" ," _" :" chromatin immunoprecipitation sequencing CXCL1" },{" #name" :" keyword" ," $" :{" id" :" kwrd0075" }," $$" :[{" #name" :" text" ," _" :" C-X-C motif chemokine 1 CXCL8" },{" #name" :" keyword" ," $" :{" id" :" kwrd0085" }," $$" :[{" #name" :" text" ," _" :" C-X-C motif chemokine 8 DSG" },{" #name" :" keyword" ," $" :{" id" :" kwrd0095" }," $$" :[{" #name" :" text" ," _" :" disuccinimidyl glutarate EC" },{" #name" :" keyword" ," $" :{" id" :" kwrd0105" }," $$" :[{" #name" :" text" ," _" :" endothelial cell ELISA" },{" #name" :" keyword" ," $" :{" id" :" kwrd0115" }," $$" :[{" #name" :" text" ," _" :" enzyme-linked immunosorbent assay EndoMT" },{" #name" :" keyword" ," $" :{" id" :" kwrd0125" }," $$" :[{" #name" :" text" ," _" :" endothelial-to-mesenchymal transition HMGCR" },{" #name" :" keyword" ," $" :{" id" :" kwrd0135" }," $$" :[{" #name" :" text" ," _" :" 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCS1" },{" #name" :" keyword" ," $" :{" id" :" kwrd0145" }," $$" :[{" #name" :" text" ," _" :" hydroxymethylglutaryl-CoA synthase 1 IL6" },{" #name" :" keyword" ," $" :{" id" :" kwrd0155" }," $$" :[{" #name" :" text" ," _" :" interleukin-6 KLF6" },{" #name" :" keyword" ," $" :{" id" :" kwrd0165" }," $$" :[{" #name" :" text" ," _" :" Krueppel-like factor 6 LDL" },{" #name" :" keyword" ," $" :{" id" :" kwrd0175" }," $$" :[{" #name" :" text" ," _" :" low-density lipoprotein LDLR" },{" #name" :" keyword" ," $" :{" id" :" kwrd0185" }," $$" :[{" #name" :" text" ," _" :" low-density lipoprotein receptor LPDS" },{" #name" :" keyword" ," $" :{" id" :" kwrd0195" }," $$" :[{" #name" :" text" ," _" :" lipoprotein depleted serum SCAP" },{" #name" :" keyword" ," $" :{" id" :" kwrd0205" }," $$" :[{" #name" :" text" ," _" :" SREBP cleavage-activating protein SREBP2" },{" #name" :" keyword" ," $" :{" id" :" kwrd0215" }," $$" :[{" #name" :" text" ," _" :" sterol response element binding protein |
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