pH-sensitive cationic lipopeptides for the design of drug-delivery systems |
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Authors: | Yu. L. Sebyakin U. A. Budanova |
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Affiliation: | (1) Lomonosov State Academy of Fine Chemical Technology, pr. Vernadskogo 86, Moscow, 119571, Russia |
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Abstract: | Lipopeptides on the basis of L-glutamic acid and glutamine di-and monoesters with aliphatic alcohols of various lengths that contain L-arginine, L-ornithine, and L-lysine were synthesized. The behavior of these amphiphiles in aqueous medium was shown to depend on their structure. |
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Keywords: | cationic amphiphiles lipopeptides delivery systems |
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