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pH-sensitive cationic lipopeptides for the design of drug-delivery systems
Authors:Yu. L. Sebyakin  U. A. Budanova
Affiliation:(1) Lomonosov State Academy of Fine Chemical Technology, pr. Vernadskogo 86, Moscow, 119571, Russia
Abstract:Lipopeptides on the basis of L-glutamic acid and glutamine di-and monoesters with aliphatic alcohols of various lengths that contain L-arginine, L-ornithine, and L-lysine were synthesized. The behavior of these amphiphiles in aqueous medium was shown to depend on their structure.
Keywords:cationic amphiphiles  lipopeptides  delivery systems
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