| 真菌环状RNA鉴定及研究展望 |
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| 引用本文： | 胡雪嫣,张赟,杨恩策,杜明昊. 真菌环状RNA鉴定及研究展望[J]. 菌物学报, 2021, 40(9): 2215-2222. DOI: 10.13346/j.mycosystema.210199 |
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| 作者姓名： | 胡雪嫣 张赟 杨恩策 杜明昊 |
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| 作者单位： | 1.北京大学医学部基础医学院医学生物信息学系 北京 1001912.北京大学医学部基础医学院病原生物学系 北京 100191 |
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| 摘 要： | 环状RNA是一类具有丰富调节潜力的闭合环状单链RNA,其可以通过竞争性结合内源RNA、充当蛋白质支架以及翻译模板等方式,从而参与基因表达调控。本文综述了真菌环状RNA的鉴定流程和难点,为后续解析环状RNA在真菌发育与代谢等过程中的调节作用提供理论支持。
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| 关 键 词： | 真菌环状RNA 环状RNA鉴定 RNA-seq数据 |
| 收稿时间： | 2021-05-24 |
CircRNA in fungi:identification procedure and research perspective |
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| HU Xue-Yan,ZHANG Yun,YANG En-Ce,DU Ming-Hao. CircRNA in fungi:identification procedure and research perspective[J]. Mycosystema, 2021, 40(9): 2215-2222. DOI: 10.13346/j.mycosystema.210199 |
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| Authors: | HU Xue-Yan ZHANG Yun YANG En-Ce DU Ming-Hao |
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| Affiliation: | 1. Department of Medical Bioinformatics, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, China2. Department of Microbiology & Infectious Disease Center, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, China |
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| Abstract: | Circular RNA is a class of covalently closed RNAs, which plays important roles in the regulation of gene expression, such as competitive endogenous RNAs, protein scaffolds, and translation templates. The processes for identifying circular RNAs in fungi are reviewed for the purposes of providing theoretical support for unravelling the regulatory role of circular RNA in fungal developments and metabolisms. |
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| Keywords: | fungal circular RNA circular RNA identification RNA-seq data |
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