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Assignment of the developmentally regulated gene NEDD1 to human chromosome 12q22 by fluorescence in situ hybridization |
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| Authors: | S Takai Y Yoshida M Noda K Yamada S Kumar |
| Institution: | (1) Department of Genetics, Research Institute, International Medical Center of Japan, 1-21-1 Toyama, Shinjuku-ku, 162 Tokyo, Japan;(2) Department of Viral Oncology, Cancer Institute, Japanese Foundation for Cancer Research, 1-37-1 Kami-Ikebukuro, Toshima-ku, 170 Tokyo, Japan;(3) Department of Molecular Oncology, Faculty of Medicine, Kyoto University, 606 Kyoto, Japan;(4) Present address: Hanson Centre for Cancer Research, Institute of Medical and Veterinary Science, PO Box 14, 5000 Rundle Mall, Adelaide, Australia |
| Abstract: | The developmentally regulated mouse gene Nedd 1 encodes a protein showing similarities with the  -subunit of heterotrimeric GTP-binding proteins and has growth suppressing activity when overexpressed in various cultured cell types. We have mapped the human homolog (NEDD1) of the mouse gene to chromosome 12q22 by fluorescence in situ hybridization using R-banded human (pro)metaphase chromosomes. |
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