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Celogentin mimetics as inhibitors of tubulin polymerization |
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| Authors: | Varsha J. Thombare James A. Holden Eric C. Reynolds Neil M. O'Brien‐Simpson Craig A. Hutton |
| Abstract: | Bicyclic analogues of celogentin C have been synthesized in which the side chain–side chain cross‐links are replaced by thioether bonds. Several of the simplified bicyclic peptides displayed potent inhibition of tubulin polymerization. |
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