Inositol 1,4,5-trisphosphate and 5'-GTP induce calcium release from different intracellular pools |
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Authors: | V Henne A Piiper H D S?ling |
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Abstract: | It has been shown recently by several groups that 5'-GTP can release calcium from intracellular compartments independently from inositol 1,4,5-trisphosphate (Ins(1,4,5)P3) by a mechanism which seems to be different from that used by Ins(1,4,5)P3. We report here for the first time that the 5'-GTP-sensitive and the Ins(1,4,5)P3-sensitive calcium pools reside in different intracellular compartments. |
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