Economic improvement of the fermentative production of gallidermin by Staphylococcus gallinarum

Gallidermin production by Staphylococcus gallinarum was optimal using a new developed medium consisting of 50 g yeast extract l^–1, 45 g CaCl₂ l^–1 and 5 g maltose l^–1. Medium optimisation led to the cost of the medium decreasing by 93% compared to the previously used medium and in addition gained a higher product yield. A scale-up of the process based on the new medium was successfully tested up to a working volume of 200 l.