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The therapeutic potential of targeting the BRAF mutation in patients with colorectal cancer
Authors:Afsane Bahrami  AmirReza Hesari  Majid Khazaei  Seyed Mahdi Hassanian  Gordon A Ferns  Amir Avan
Institution:1. Department of Modern Sciences and Technologies, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran;2. Student Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran;3. Department of Biology, Damghan Branch, Islamic Azad University, Damghan, Iran;4. Department of Physiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran;5. Metabolic syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran;6. Department of Medical Biochemistry, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran;7. Division of Medical Education, Brighton and Sussex Medical School, Falmer, Brighton, UK;8. Cancer Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
Abstract:
Keywords:BRAF mutation  colorectal cancer  RAS/RAF/MEK/ERK pathway  target therapy
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