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GSK‐3β inhibition suppresses instability‐induced osteolysis by a dual action on osteoblast and osteoclast differentiation
Authors:Mehdi Amirhosseini  Rune V Madsen  K Jane Escott  Mathias P Bostrom  F Patrick Ross  Anna Fahlgren
Institution:1. Division of Cell Biology, Department of Clinical and Experimental Medicine, Link?ping University, Link?ping, Sweden;2. Adult Reconstruction and Joint Replacement Service, Hospital for Special Surgery, New York, New York;3. Scientific Partnering & Alliances, Innovative Medicines and Early Development Biotech Unit, AstraZeneca, Melbourn, UK
Abstract:
Keywords:bone implant  GSK‐3β    mechanical instability  osteolysis  Wnt signaling
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