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Simvastatin induces G1 arrest by up‐regulating GSK3β and down‐regulating CDK4/cyclin D1 and CDK2/cyclin E1 in human primary colorectal cancer cells |
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| Authors: | Ming‐Jenn Chen An‐Ching Cheng Ming‐Fen Lee Yi‐Chiang Hsu |
| Institution: | 1. Department of Surgery, Chi‐Mei Medical Center, Tainan, Taiwan;2. Department of Sports Management, College of Leisure and Recreation Management, Chia Nan University of Pharmacy and Science, Tainan, Taiwan;3. Department of Nutrition and Health Sciences, Chang Jung Christian University, Tainan, Taiwan;4. Department of Medical Sciences Industry, College of Health Sciences, Chang Jung Christian University, Tainan, Taiwan |
| Abstract: | |
| Keywords: | colorectal cancer cyclin D1 G1 arrest glycogen synthase kinase 3β simvastatin |