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The xenoestrogens biphenol‐A and nonylphenol differentially regulate metalloprotease‐mediated shedding of EGFR ligands
Authors:Paulina Urriola‐Muñoz  Xue Li  Thorsten Maretzky  David R. McIlwain  Tak W. Mak  Juan G. Reyes  Carl P. Blobel  Ricardo D. Moreno
Affiliation:1. Facultad de Ciencias Biológicas, Departamento de Fisiología, Pontificia Universidad Católica de Chile, Santiago, Chile;2. Instituto de Química, Pontificia Universidad Católica de Valparaíso, Valparaíso, Chile;3. Arthritis and Tissue Degeneration Program, Hospital for Special Surgery, New York, New York;4. Department of Biochemistry, Cellular and Molecular Biology, Weill Cornell Graduate School of Medical Sciences, New York, New York;5. Department of Microbiology and Immunology, Baxter Laboratory in Stem Cell Biology, Stanford University, Stanford, California;6. Campbell Family Institute for Breast Cancer Research, Princess Margaret Cancer Center, University Health Network, Toronto, Ontario, Canada;7. Institute for Advanced Study, Technische Universit?t München, Garching, Germany;8. Department of Physiology, Biophysics and Systems Biology, Weill Cornell University, New York, New York
Abstract:
Keywords:ADAM  epidermal growth factor receptor (EGFR)  growth factor  xenobiotic
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