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Kinetic characterisation of o-aminophenols and aromatic o-diamines as suicide substrates of tyrosinase |
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| Authors: | Muñoz-Muñoz Jose Luis Garcia-Molina Francisco Berna Jose Garcia-Ruiz Pedro Antonio Varon Ramon Tudela Jose Rodriguez-Lopez Jose N Garcia-Canovas Francisco |
| Institution: | GENZ: Grupo de Investigación Enzimología, Departamento de Bioquímica y Biología Molecular-A, Facultad de Biología, Universidad de Murcia, E-30100, Espinardo, Murcia, Spain. |
| Abstract: | We study the suicide inactivation of tyrosinase acting on o-aminophenols and aromatic o-diamines and compare the results with those obtained for the corresponding o-diphenols. The catalytic constants follow the order aromatic o-diamines |
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