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Laminin: the crux of basement membrane assembly
Authors:Sasaki Takako  Fässler Reinhard  Hohenester Erhard
Institution:Department of Molecular Medicine, Max Planck Institute of Biochemistry, Martinsried, Germany.
Abstract:Laminin-1 is emerging as the key molecule in early embryonic basement membrane assembly. Here we review recent insights into its functions gained from the synergistic application of genetic and structural methods.
Keywords:extracellular matrix  embryo development  mutagenesis  structure determination
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