SigE is a chaperone for the Salmonella enterica serovar Typhimurium invasion protein SigD |
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| Authors: | Darwin K H Robinson L S Miller V L |
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| Affiliation: | Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri 63110, USA. |
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| Abstract: | SigD is translocated into eucaryotic cells by a type III secretion system. In this work, evidence that the putative chaperone SigE directly interacts with SigD is presented. A bacterial two-hybrid system demonstrated that SigE can interact with itself and SigD. In addition, SigD was specifically copurified with SigE-His(6) on a nickel column. |
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