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Genomic analysis of Campylobacter fetus subspecies: identification of candidate virulence determinants and diagnostic assay targets |
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| Authors: | Paula M Moolhuijzen Ala E Lew-Tabor Bartosz M Wlodek Fernán G Agüero Diego J Comerci Rodolfo A Ugalde Daniel O Sanchez Rudi Appels and Matthew Bellgard |
| Institution: | (1) Centre for Comparative Genomics, School for Information Technology, Murdoch University, Murdoch, Western Australia, Australia;(2) Emerging Technologies, Queensland Department of Primary Industries Fisheries, Yeeongpilly, Queensland, Australia;(3) Instituto de Investigaciones Biotecnol?gicas, Universidad Nacional de General San Mart?n - CONICET, 1650 KNA, San Martn, Buenos Aires, Argentina |
| Abstract: | BackgroundCampylobacter fetus subspecies venerealis is the causative agent of bovine genital campylobacteriosis, asymptomatic in bulls the disease is spread to female cattle causing extensive reproductive loss. The microbiological and molecular differentiation of C. fetus subsp. venerealis from C. fetus subsp. fetus is extremely difficult. This study describes the analysis of the available C. fetus subsp. venerealis AZUL-94 strain genome (~75–80%) to identify elements exclusively found in C. fetus subsp. venerealis strains as potential diagnostic targets and the characterisation of subspecies virulence genes. |
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