Transient transport across the blood-retina barrier |
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| Authors: | Jesper Larsen Henrik Lund-Andersen Bent Krogsaa |
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| Institution: | (1) MATH-TECH Institute, Sommervej 7, DK-2920 Charlottenlund, Denmark;(2) University Eye Clinic, Rigshospitalet, E2061, DK-2100 Copenhagen, Denmark |
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| Abstract: | A mathematical model of the transport of fluorescein across the blood-retina barrier in the transient state and the subsequent
diffusion of fluorescein in the vitreous body is presented. The function of the barrier is lumped in a single parameter—the
permeability. The sensitivity of this parameter due to changes in the other parameters of the model is given. This establishes
the foundation for the quantitative assessment of the barrier function through vitreous fluorophotometry. |
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