Locations of a Human Satellite DNA in Human Chromosomes |
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Authors: | GRADY F. SAUNDERS T. C. HSU MICHAEL J. GETZ E. LEE SIMES FRANCES E. ARRIGHI |
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Affiliation: | 1.Departments of Developmental Therapeutics and Biology,University of Texas at Houston M. D. Anderson Hospital and umor Institute and Graduate School of Biomedical Sciences,Houston |
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Abstract: | USING techniques for DNA/RNA or DNA/DNA hybridization in situ, Pardue and Gall1 and Jones2 made several significant discoveries on the chromosomal locations of the mouse satellite DNA: (1) this fraction of DNA is found in all chromosomes except the Y, (2) the cytological location of the satellite DNA is limited to the centromeric region of each chromosome and is probably absent in other regions and (3) the centromeric regions of all mouse chromosomes are hetero-chromatic. |
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