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Gene Triplication deduced from the Tertiary Structure of a Muscle Calcium Binding Protein
Authors:R H KRETSINGER
Institution:1.Department of Biology,University of Virginia,Charlottesville
Abstract:GENE duplication was first observed cytologically in the bar gene of drosophila1. The idea, extended by Dixon2, has been used to explain the obvious repeats in amino-acid sequence in the immunoglobulins, in bacterial ferredoxins, in haptoglobin α-2 (summarized in ref. 3) and in neurophysin4.
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