Degradation of adenine nucleotides in the erythrocytes of patients with chronic renal failure |
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Authors: | R T Smoleński M Marlewski |
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Affiliation: | Department of Biochemistry, Academic Medical School of Gdańsk, Poland. |
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Abstract: | In chronic renal failure AMP-deaminase operates in the erythrocytes at a much higher velocity than in healthy subjects, with a simultaneous shift from the AMP-adenine-inosine-hypoxanthine pathway (55% and 19%, respectively) to the pathway initiated by AMP-deaminase (45% and 81%, respectively). |
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