ApA Dinucleotide Periodicity in Prokaryote, Eukaryote, and Organelle Genomes |
| |
Authors: | Masaru Tomita Masahiko Wada Yukihiro Kawashima |
| |
Affiliation: | (1) Laboratory for Bioinformatics, Keio University, 5322 Endo, Fujisawa, Kanagawa 252-8520, Japan, JP;(2) Department of Environmental Information, Keio University, 5322 Endo, Fujisawa, Kanagawa 252-8520, Japan, JP;(3) Graduate School of Media and Governance, Keio University, 5322 Endo, Fujisawa, Kanagawa 252-8520, Japan, JP |
| |
Abstract: | Computer analyses of various genome sequences revealed the existence of certain periodical patterns of adenine–adenine dinucleotides (ApA). For each genome sequence of 13 eubacteria, 3 archaebacteria, 10 eukaryotes, 60 mitochondria, and 9 chloroplasts, we counted frequencies of ApA dinucleotides at each downstream position within 50 bp from every ApA. We found that the complete genomes of all three archaebacteria have clear ApA periodicities of about 10 bps. On the other hand, all of the 13 eubacteria we analyzed were found to have an ApA periodicity of about 11 bp. Similar periodicities exist in the 10 eukaryotes, although higher organisms such as primates tend to have weaker periodic patterns. None of the mitochondria and chroloplasts we analyzed showed an evident periodic pattern. Received: 3 November 1998 / Accepted: 24 March 1999 |
| |
Keywords: | : Dinucleotide — Sequence periodicity — Complete genome — Mitochondria — Chroloplast — Prokaryote — Eukaryote |
本文献已被 SpringerLink 等数据库收录! |
|