The effect of somatostatins (SRIF-14, 25 and 28), galanin and anti-SRIF on plasma growth hormone levels in Coho salmon (Oncorhynchus kisutch, Walbaum) |
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| Authors: | J. M. Diez,G. Giannicot,&dagger ,E. McLeant,&dagger E. M. Donaldson,&dagger &Dagger |
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| Affiliation: | Departmento de Bioquimica y Biologia Molecular y Fisiologia, Universidad de Valladolid, 47005 Valladolid, Spain;Department of Fisheries and Oceans, West Vancouver Laboratory, 4160 Marine Drive, West Vancouver, B.C. V7V 1N6, Canada |
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| Abstract: | Porcine galanin, somatostatins (SRIF-25 and SRIF-28) and invariant SRIF-14, known to have inhibitory-stimulatory actions on growth hormone (GH) secretion in higher vertebrates, were tested for their ability to affect plasma GH levels in coho salmon. Peptides were administered by intraperitoneal injection of 10 or 100 ng g−1 body weight. All three SRIFs decreased plasma GH concentrations, their activity following the order SRIF-14 > SRIF-28 > SRIF-25. Galanin and an anti-SRIF produced pronounced, although transient increases in plasma GH. |
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| Keywords: | somatotropin release inhibitory factor (SRIF) SRIF-14 SRIF-25 SRIF-28 anti-somatotropin release inhibitory factor growth hormone coho salmon Oncorhynchus kisulch |
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