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Enhanced CellClassifier: a multi-class classification tool for microscopy images
Authors:Benjamin Misselwitz  Gerhard Strittmatter  Balamurugan Periaswamy  Markus C Schlumberger  Samuel Rout  Peter Horvath  Karol Kozak  Wolf-Dietrich Hardt
Institution:1.Institute of Microbiology,ETH Zurich,Zürich,Switzerland;2.Light Microscopy Centre, Institute of Biochemistry,ETH Zürich,Zürich,Switzerland
Abstract:

Background  

Light microscopy is of central importance in cell biology. The recent introduction of automated high content screening has expanded this technology towards automation of experiments and performing large scale perturbation assays. Nevertheless, evaluation of microscopy data continues to be a bottleneck in many projects. Currently, among open source software, CellProfiler and its extension Analyst are widely used in automated image processing. Even though revolutionizing image analysis in current biology, some routine and many advanced tasks are either not supported or require programming skills of the researcher. This represents a significant obstacle in many biology laboratories.
Keywords:
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