Spatial discontinuity of Optomotor-blind expression in the <Emphasis Type="Italic">Drosophila</Emphasis> wing imaginal disc disrupts epithelial architecture and promotes cell sorting |
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| Authors: | Jie Shen Christian Dahmann Gert O Pflugfelder |
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| Institution: | (1) Dept of Entomology, China Agricultural University, 100094 Beijing, China;(2) Institute of Genetics, Johannes Gutenberg University Mainz, 55128 Mainz, Germany;(3) Max Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany |
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| Abstract: | Background Decapentaplegic (Dpp) is one of the best characterized morphogens, required for dorso-ventral patterning of the Drosophila embryo and for anterior-posterior (A/P) patterning of the wing imaginal disc. In the larval wing pouch, the Dpp target gene
optomotor-blind (omb) is generally assumed to be expressed in a step function above a certain threshold of Dpp signaling activity. |
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