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Cholesterol homeostasis regulated by ABCA1 is critical for retinal ganglion cell survival |
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| Authors: | Yang Jialiang Chen Yuhong Zou Tongdan Xue Bai Yang Fang Wang Xiangzhou Huo Yibo Yan Boyun Xu Yuxia He Shiyu Yin Yi Wang Jing Zhu Xiong Zhang Lin Zhou Yu Tai Zhengfu Shuai Ping Yu Man Luo Qian Cheng Yilian Gong Bo Zhu Xianjun Zhang Jing Sun Xinghuai Lin Ying Zhang Houbin Yang Zhenglin |
| Affiliation: | 1.Key Laboratory for Human Disease Gene Study of Sichuan Province and Institute of Laboratory Medicine, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, 610072, China ;2.Department of Ophthalmology and Visual Science, Eye and Ear Nose Throat (ENT) Hospital, Fudan University, Shanghai, 200032, China ;3.School of Optoelectronic Science and Engineering, University of Electronic Science and Technology of China, Chengdu, 611731, China ;4.Institute of Chengdu Biology, Sichuan Translational Medicine Hospital, Chinese Academy of Sciences, Chengdu, 610093, China ;5.Department of Ophthalmology, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, 610072, China ;6.Research Unit for Blindness Prevention of Chinese Academy of Medical Sciences, Sichuan Academy of Medical Sciences & Sichuan Provincial People’s Hospital, Chengdu, 610072, China ; |
| Abstract: | Science China Life Sciences - Genome-wide association studies have suggested a link between primary open-angle glaucoma and the function of ABCA1. ABCA1 is a key regulator of cholesterol efflux and... |
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