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Snapshot of HIV pathogenesis in China
引用本文:Nitin K SAKSENA,Megan STEAIN. Snapshot of HIV pathogenesis in China[J]. Cell research, 2005, 0(Z1)
作者姓名:Nitin K SAKSENA  Megan STEAIN
作者单位:Retroviral Genetics Division Centre for Virus Research Westmead Millennium Institute The University of Sydney Westmead NSW 2145 Sydney Australia,Retroviral Genetics Division Centre for Virus Research Westmead Millennium Institute The University of Sydney Westmead NSW 2145 Sydney Australia
摘    要:INTRODUCTION A recent report by the National Intelligence Council es- timates that by 2010 five countries, India, China, Nigeria, Ethiopia and Russia, cumulatively, will harbor the largest number of individuals infected with the Human Immuno- deficiency V…


Snapshot of HIV pathogenesis in China
Abstract:Several reviews have focused on the nature of HIV infection and its spread in various geographical regions of China. In contrast, this review provides a comprehensive update on the prevalence of multiple HIV-1 subtypes, consequent emergence of recombinant and novel forms of HIV-1 in China, and the implications this may have on HIV diversity and the development of effective vaccines. In addition it also examines the dissemination of primary drug resistance in therapy na?ve patients, as well as co-infections with two other important viruses-hepatitis B and C. The main purpose of this review is to provide a current snapshot of HIV-1 pathogenesis in China and possibly shed some light on the future of HIV evolution, and potential challenges for future vaccine and anti-retroviral therapeutics against HIV strains in this area.
Keywords:HIV   recombination   circulating recombinant forms   co-infections   AIDS.
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