Changes in the esterase activity and isoenzyme spectrum following the transplantation of embryonic nerve tissue into the brain of adult rats

Nervous tissue of 17-days old rat embryos was transplanted into lateral ventricle of the brain of adult rats. 15 days after transplantation esterase activity was analyzed from transplant tissue and flanking regions of cerebral cortex. Isoenzymes were shown to activate their activity after embryonic tissue transplantation either in transplants or flanking regions. These changes result obviously from the effect of substances, synthesized by transplant.