| 利用乳酸菌降解草酸预防结石的研究进展 |
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| 引用本文： | 董婷婷,袁杰利.利用乳酸菌降解草酸预防结石的研究进展[J].中国微生态学杂志,2011,23(3):266-267,271. |
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| 作者姓名： | 董婷婷 袁杰利 |
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| 作者单位： | 大连医科大学,微生态教研室,辽宁,大连,116044 |
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| 基金项目： | 国家“863”计划(2007A10Z356); 国家“973”计划(2007CB513007) |
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| 摘 要： | 人体中尿草酸浓度过高是引起泌尿系统结石的一个重要因素。泌尿系统结石的形成受到遗传、环境、饮食、药物和疾病等多方面因素的影响。人体中尿草酸浓度过高,对肾上皮细胞具有毒性,并造成上皮的损伤,同时上皮细胞也主动摄入晶体、分泌大分子物质,二者相互作用最终导致结石的形成。降低尿草酸的浓度是预防泌尿系统疾病的重要因素。国内外研究发现乳酸菌具有降解草酸的能力,乳酸菌是益生菌,具有较好的生物安全性,可成为临床预防草酸钙结石的有效途径。
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| 关 键 词： | 乳酸菌 草酸 尿石症 |
Research progress on urolithiasis prevantion via oxalate degradation |
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| DONG Ting-ting,YUAN Jie-li.Research progress on urolithiasis prevantion via oxalate degradation[J].Chinese Journal of Microecology,2011,23(3):266-267,271. |
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| Authors: | DONG Ting-ting YUAN Jie-li |
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| Institution: | DONG Ting-ting,YUAN Jie-li (Department of Microecology,Dalian Medical University,Dalian 116044,China) |
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| Abstract: | The high concentration of oxalic acid in human urine is an important factor for a urinary stone.The formation of the urinary stone is influenced by heredity,environment and food,medicine,sickness and many factors.If the concentration of oxalic acid in human urine is too high,it will hurt the Kidney epithelial cell.The interaction between oxalate and epithelial cells produces poisonous substance,which hurt epidermis.The epithelial cells also intake crystal and excrete macromolecule substance.The interaction ... |
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| Keywords: | Lactic acid bacteria Oxalate Urolithiasis |
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