Effects of short term experimental diabetes on brain serotonin metabolism |
| |
| Authors: | G Atienza M Aldegunde R Durán J A Veira |
| |
| Institution: | Departamento de Fisiología, Facultad de Biología, Santiago de Compostela, Spain. |
| |
| Abstract: | Serotonin metabolism was studied in several brain regions of control and Streptozotocin-treated male Wistar rats. After induction of diabetes, the animals were killed at 24 hours. Concentrations of brain tryptophan show a generalized increase in all brain regions, being only significant in medulla-pons. Serotonin levels do not change, while 5-HIAA concentrations, as well as the ratio 5-HIAA/5-HT, show significant increases in medulla-pons and mid-brain. |
| |
| Keywords: | |
|
|
