A Phosphodiesterase from Ascites Carcinoma Krebs II Cells Specifically Cleaves the Bond between VPg and RNA of Encephalomyocarditis Virus期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

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A Phosphodiesterase from Ascites Carcinoma Krebs II Cells Specifically Cleaves the Bond between VPg and RNA of Encephalomyocarditis Virus

Authors:	A Yu Gulevich R A Yusupova Yu F Drygin

Institution:	(1) Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, 119899, Russia

Abstract:	The substrate specificity of the unlinking enzyme from ascites carcinoma Krebs II cells has been investigated. The enzyme specifically splits the interpolymeric phosphodiester bond between Kp and the 5´-terminal phosphate group of the uridylic acid residue in the Kp–pUpUpGp complex.

Keywords:	picornavirus VPg– RNA unlinkinggif" alt="ldquo" align="MIDDLE" BORDER="0">unlinking enzyme" target="_blank">gif" alt="rdquo" align="MIDDLE" BORDER="0"> enzyme substrate specificity phosphodiesterase
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