Characterization of a novel mucin sulphotransferase activity synthesizing sulphated O-glycan core 1, 3-sulphate-Gal{beta}1-3GalNAc{alpha}-R |
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Authors: | Kuhns, William Jain, Rakesh K. Matta, Khushi L. Paulsen, Hans Baker, Michael A. Geyer, Rudolf Brockhausen, Inka |
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Affiliation: | 1Research Institute, The Hospital for Sick Children Toronto, Ontario, M5G IX8, Canada 2Roswell Park Memorial Institute Buffalo, NY, USA 3Institut für Organische Chemie, Universität Hamburg Hamburg, FRG 4Department of Medicine, Toronto General Hospital and University of Toronto Toronto, Ontario, Canada 5Biochemisches Institut, Justus Liebig Universität GieBen, FRG 6Department of Biochemistry, University of Toronto Toronto, Ontario, Canada |
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Abstract: | A novel sulphotransferase (sulpho-T) activity from rat colonicmucosa was characterized using O-glycan core 1 substrate, Galß1-3GalNAc |
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