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SAMMate: a GUI tool for processing short read alignments in SAM/BAM format |
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| Authors: | Guorong Xu Nan Deng Zhiyu Zhao Thair Judeh Erik Flemington Dongxiao Zhu |
| Institution: | (1) Department of Computer Science, University of New Orleans, 2000 Lakeshore Drive, New Orleans, LA 70148, USA;(2) Tulane Cancer Center and Tulane Health Science Center, 1430 Tulane Ave, New Orleans, LA 70112, USA;(3) The Research Institute for Children, Children’s Hospital, 200 Henry Clay Ave, New Orleans, LA 70118, USA |
| Abstract: | BackgroundNext Generation Sequencing (NGS) technology generates tens of millions of short reads for each DNA/RNA sample. A key step in NGS data analysis is the short read alignment of the generated sequences to a reference genome. Although storing alignment information in the Sequence Alignment/Map (SAM) or Binary SAM (BAM) format is now standard, biomedical researchers still have difficulty accessing this information. |
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